Development of a More Thermostable Poliovirus Vaccine
نویسندگان
چکیده
منابع مشابه
Development of a more thermostable poliovirus vaccine.
In 1991, a goal of improved thermostability of oral poliovirus vaccine (OPV) was set, and the Product Development Group was established under the Children's Vaccine Initiative to achieve this goal. Several initial research strategies were unsuccessful. The substitution of deuterium oxide for water in the final blending stage of vaccine production resulted in a significantly more stable product ...
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Influenza viruses continue to be a major health threat in human and bird populations. The improvements in formulation and production level of the current influenza vaccines are not sufficient to afford complete protection. The continuous antigenic drifts and emergence of endemic and zoonotic strains make influenza vaccine planning difficult. Concern about the emergence of new influenza pandemic...
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I have spent a great part of m y life in the pursuit of knowledge about the natural history of poliomyelitis and in the development of vaccines that may give m an the power to eliminate this disease as a source of human misery. On this occasion I have, therefore, chosen to present to you not a detailed analysis of isolated observations, which are already available for criticai evaluation in the...
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David Bodian spent almost his whole scientific career (1942–1983) at the Johns Hopkins University, first in the Department of Epidemiology at the School of Hygiene and Public Health and then in the Department of Anatomy at the School of Medicine. Arguably, his most important research contribution was the elucidation of the pathogenesis of poliomyelitis—a contribution that played a major role in...
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This study compares the presence of environmental poliovirus in two Argentinean populations using oral poliovirus vaccine (OPV) or inactivated poliovirus vaccine (IPV). From January 2003 to December 2005, Córdoba City used IPV in routine infant immunizations, with the exception of intermittent OPV use in August 2005. Between May 2005 and April 2006, we collected weekly wastewater samples in Cór...
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ژورنال
عنوان ژورنال: Journal of Infectious Diseases
سال: 1997
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/175.supplement_1.s247